Medical dictionary
Medical terminology normalized via MeSH, ICD-11, SNOMED CT.
62,341 terms indexed
RefSeq NM_027434
A mild form of LIMITED SCLERODERMA, a multi-system disorder. Its features include symptoms of CALCINOSIS; RAYNAUD DISEASE; ESOPHAGEAL MOTILITY DISORDERS; sclerodactyly, and TELANGIECTASIS. When the defect in esophageal function is not prominent, it is known as CRST syndrome.
RefSeq NM_178750
RefSeq NM_116028
GenBank EF014952
GenBank EU882845
has two LCCL domains; RefSeq XP_003199065
Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.
Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR elements) that function in conjunction with CRISPR-ASSOCIATED PROTEINS (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-ASSOCIATED PROTEINS.
No RefSeq available
RefSeq NM_169071
RefSeq NR_034105
RefSeq NM_001101426
interacts with CRR4 protein; involved with RNA editing; RefSeq NM_130098
CRS - Cdf-related gene Responsive to Senescence; Cdf - Cell Growth Defect factor 1; promotes plant senescence by increasing the production of hydrogen peroxide
structure in first source
CRT1 - compromised for recognition of Turnip Crinkle virus (or compromised recognition of TCV); a MORC endonuclease; RefSeq NM_119797
1
a sphingosine-1-phosphate receptor modulator
structure in first source
RefSeq NM_001277059
RefSeq NM_100757
RefSeq NM_128379
a potent and selective cathepsin S inhibitor; structure in first source
has anti-inflammatory activity; structure in first source
formulation of hApoA-I designed to remove cholesterol from atherosclerotic plaques of coronary heart disease patients
RefSeq NM_128870
RefSeq NM_121697
RefSeq NM_119980
RefSeq NM_053171
subunit of COP9 signalosome; RefSeq NM_079727
RefSeq NM_001895; CK2alpha' is paralogous isoform
a nonantibiotic with anti-inflammatory activity; structure in first source
SDF-1alpha peptide analog and CXCR4 agonist; structure in first source
RefSeq NM_199544
RefSeq NM_119289
RefSeq NM_014772
An inhibitory T CELL receptor that is closely related to CD28 ANTIGEN. It has specificity for CD80 ANTIGEN and CD86 ANTIGEN and acts as a negative regulator of peripheral T cell function. CTLA-4 antigen is believed to play role in inducing PERIPHERAL TOLERANCE.
RefSeq NM_001204129
RefSeq NM_153155
RefSeq NM_080285
structure in first source
a vascular leakage blocker; structure in first source