Medical dictionary
Medical terminology normalized via MeSH, ICD-11, SNOMED CT.
62,341 terms indexed
RefSeq NM_017845
RefSeq NM_000754
an anti-EGFR nanobody with antineoplastic activity
TRANSPORT VESICLES formed when cell-membrane coated pits (COATED PITS, CELL-MEMBRANE) invaginate and pinch off. The outer surface of these vesicles is covered with a lattice-like network of COP (coat protein complex) proteins, either COPI or COPII. COPI coated vesicles transport backwards from the cisternae of the GOLGI APPARATUS to the rough endoplasmic reticulum (ENDOPLASMIC RETICULUM, ROUGH), while COPII coated vesicles transport forward from the rough endoplasmic reticulum to the Golgi apparatus.
RefSeq NM_006710
a copper transporter; RefSeq NM_114557
RefSeq NM_179760
RefSeq NM_032314
RefSeq NM_024876
CELL LINES derived from the CV-1 cell line by transformation with a replication origin defective mutant of SV40 VIRUS, which codes for wild type large T antigen (ANTIGENS, POLYOMAVIRUS TRANSFORMING). They are used for transfection and cloning. (The CV-1 cell line was derived from the kidney of an adult male African green monkey (CHLOROCEBUS AETHIOPS).)
a crossover-promoting protein; RefSeq NM_065206
A COUP transcription factor that was originally identified as a homodimer that binds to a direct repeat regulatory element in the chicken albumin promoter. It is a transcription factor that plays an important role in EMBRYONIC DEVELOPMENT of the CENTRAL NERVOUS SYSTEM.
A COUP transcription factor that negatively regulates GENETIC TRANSCRIPTION and competes with other hormone receptors for the common response element AGGTCA. It can also stimulate transcription of genes involved in the metabolism of GLUCOSE and CHOLESTEROL.
A sub-family of steroid receptor-related orphan nuclear receptors that have specificity for a variety of DNA sequences related to AGGTCA. COUP transcription factors can heterodimerize with a variety of factors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; and VITAMIN D RECEPTORS.
a copper chaperone for cytochrome c oxidase; RefSeq NM_001109575
RefSeq NM_032901
RefSeq NM_004255
structure in first source
a neuropeptide Y1 receptor antagonist; structure in first source
a tissue apoptosis PET imaging agent; structure in first source
antineoplastic polyketide found in Soranium sp.; structure in first source
RefSeq NM_118610
a synthetic peptide; an HIV-1 fusion inhibitor
RefSeq NM_020361
RefSeq NM_001872
RefSeq NM_122264
RefSeq NM_128707
RefSeq NM_119697
RefSeq NM_023073
RefSeq NM_001030005
NM_062335 (isoform b)
involved in glucose uptake in adipocytes; RefSeq NM_001099455 (isoform b)
RefSeq NM_001180462
RefSeq NM_121862
prevents intestinal barrier dysfunction
RefSeq NM_001876
RefSeq NM_001029885
structure in first source
caprazamycin derivative; structure in first source
antineoplastic
antineoplastic
pan-histone deacetylase inhibitor; structure in first source
an adjuvant for monoclonal antibody therapy
A death domain receptor signaling adaptor protein that plays a role in signaling the activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds to and activates CASPASES such as CASPASE 2.
an anti-inflammatory agent; structure in first source
A member of the p300-CBP transcription factor family that was initially identified as a binding partner for CAMP RESPONSE ELEMENT-BINDING PROTEIN. Mutations in CREB-binding protein are associated with RUBINSTEIN-TAYBI SYNDROME.