Medical dictionary
Medical terminology normalized via MeSH, ICD-11, SNOMED CT.
62,341 terms indexed
inhibits both methylthioadenosine phosphorylase and methylthioadenosine-S-adenosylhomocysteine nucleosidase; structure in first source
inhibits both methylthioadenosine phosphorylase and methylthioadenosine-S-adenosylhomocysteine nucleosidase; structure in first source
has antinociceptive activity; structure in first source
structure in first source
a fatty acid labeling reagent; structure in first source
structure in first source
structure in first source
structure in first source
a PRMT3 inhibitor; structure in first source
- C5837751-(benzofuran-2-yl(phenyl)methyl)-3-(2-(4-methoxyphenyl)-2-oxoethyl)-1H-benzo(d)imidazol-3-iumMeSH
structure in first source
- C5837741-(benzofuran-2-yl(phenyl)methyl)-3-(2-(naphthalen-2-yl)-2-oxoethyl)-1H-benzo(d)imidazol-3-iumMeSH
structure in first source
structure in first source
structure in first source
structure in first source
structure in first source
a fluorescent phototrigger for cell imaging; structure in first source
an S1P1/3 receptor antagonist prodrug; structure in first source
structure in first source
a dual norepinephrine-dopamine transporter inhibitor
structure in first source
structure in first source
structure in first source
structure in first source
structure in first source
structure in first source
An enzyme that catalyzes the acyl group transfer of ACYL COA to 1-acyl-sn-glycerol 3-phosphate to generate 1,2-diacyl-sn-glycerol 3-phosphate. This enzyme has alpha, beta, gamma, delta and epsilon subunits.
An enzyme localized predominantly within the plasma membrane of lymphocytes. It catalyzes the transfer of long-chain fatty acids, preferentially unsaturated fatty acids, to lysophosphatides with the formation of 1,2-diacylglycero-3-phosphocholine and CoA. EC 2.3.1.23.
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.
A four carbon linear hydrocarbon that has a hydroxy group at position 1.
Found in various tissues, particularly in four blood-clotting proteins including prothrombin, in kidney protein, in bone protein, and in the protein present in various ectopic calcifications.
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
A suspected industrial carcinogen (and listed as such by OSHA). Its N-hydroxy metabolite is strongly carcinogenic and mutagenic.
A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis chronically, with changes in hepatocyte function. It may cause skin and kidney damage.
from fresh leaves of Psidium guajava L.; structure in first source
a beta-glucuronidase PET imaging agent; structure in first source
an immunostimulator; structure in first source
- C5744801-O-beta-D-glucopyranosyl-(2S,3S,4R,9Z)-2-((2R)-2-hydroxydocosanoylamino)-9-octadecene-1,3,4-triolMeSH
from the roots of Livistona chinensis; structure in first source
- C5744811-O-beta-D-glucopyranosyl-(2S,3S,4R,9Z)-2-((2R)-2-hydroxytetracosanoylamino)-1,3,4-octadecanetriolMeSH
from the roots of Livistona chinensis; structure in first source
from Gentianopsis paludosa Ma; structure in first source
from Alchornea trewioides; structure in first source
a SK3 channel inhibitor
an analog of platelet activating factor (PAF); structure in first source
structure in first source
A colorless, slightly viscous liquid used as a defoaming or wetting agent. It is also used as a solvent for protective coatings, waxes, and oils, and as a raw material for plasticizers. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
An enzyme that catalyzes the conversion of phosphatidylinositol (PHOSPHATIDYLINOSITOLS) to phosphatidylinositol 4-phosphate, the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.
A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
An enzyme that catalyzes the oxidation of 1-pyrroline-5-carboxylate to L-GLUTAMATE in the presence of NAD. Defects in the enzyme are the cause of hyperprolinemia II.