Medical dictionary
Medical terminology normalized via MeSH, ICD-11, SNOMED CT.
62,341 terms indexed
A member of the tumor necrosis factor receptor superfamily found on mature B-LYMPHOCYTES. It has specificity for B CELL ACTIVATING FACTOR and TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
A classification of B-lymphocytes based on structurally or functionally different populations of cells.
Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.
B-cells that have a role in regulating the immune response including the production of CYTOKINES. This function is in addition to their traditional role in making antibodies.
structure in first source
structure in first source
a branched antimicrobial peptide; structure with amino acid sequence in first source
structure in first source
RefSeq NM_033167
RefSeq NM_019737
A family of cell-surface proteins found on ANTIGEN-PRESENTING CELLS. B7 antigens are ligands for specific cell surface receptor subtypes found on T-CELLS. They play an immunomodulatory role by stimulating or inhibiting the T-CELL activation process.
A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.
a long non-coding RNA; RefSeq NR_037803
RefSeq NM_001128195
RefSeq NM_001080519
RefSeq NM_003933
Cell lines developed from disaggregated BALB/c mouse embryos. They are extremely sensitive to CONTACT INHIBITION, and highly susceptible to transformation by SV40 VIRUS and murine sarcoma virus (SARCOMA VIRUSES, MURINE).
derived from proenkephalin A; augments Adrenocorticotropic Hormone-induced glucocorticoid secretion
RefSeq NM_118146
a beta-amylase-like protein with weak catalytic activity; RefSeq NM_130151
a beta-amylase-like protein with weak catalytic activity; RefSeq NM_123898
a folding variant of bovine alpha-lactalbumin in complex with oleic acid; has antineoplastic activity
RefSeq NM_001033350
RefSeq NM_027088
RefSeq NM_028967
a riociguat metabolite that activates soluble guanylate cyclase
antineoplastic agent that targets carbonic anhydrase IX; consists of monoclonal antibody 3ee9 conjugated to monomethyl auristatin E
a factor VIIa variant for treating hemophilia
(68)Ga-bombesin antagonist
structure in first source
RefSeq NM_028284
RefSeq NM_027810
RefSeq NM_178415
BBS - Bardet-Biedl syndrome; RefSeq XM_002664792
RefSeq NM_113009
an estrogen receptor alpha-1 antagonist; structure in first source; do not confuse with BC-I compound
an Fbxo3 inhibitor; structure in first source
RefSeq NM_143339
RefSeq NM_025392