B7-1 Antigen
MESHD018122
A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
Synonyms
- B7 1 Antigen
- Antigen, B7-1
- Antigen, B7 1
- B7-1 Ligand
- B7 1 Ligand
- Ligand, B7-1
- B-Cell Activation Antigen
- B Cell Activation Antigen
- CD80 Antigen
- CD80 Antigens
- Antigens, CD80
- B7-1 Costimulatory Molecule
- B7 1 Costimulatory Molecule
- Costimulatory Molecule, B7-1
Source last updated 2026-05-24T15:25:50.894Z