Từ điển y khoa
Thuật ngữ y khoa chuẩn hóa theo MeSH, ICD-11, SNOMED CT.
62,341 terms indexed
Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.
A group of cells that includes FIBROBLASTS, cartilage cells, ADIPOCYTES, smooth muscle cells, and bone cells.
A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.
A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.
Localized dermal malformations (HARMATOMAS) that consist of COLLAGEN; ELASTIC TISSUE; or GLYCOSAMINOGLYCANS. They may be observed on the torso of young children with inherited disorders such as TUBEROUS SCLEROSIS, or as idiopathic isolated lesions. OMIM: 166700
A comprehensive map of the physical interconnections of an organism's neural networks. This modular organization of neuronal architecture is believed to underlie disease mechanisms and the biological development of the CENTRAL NERVOUS SYSTEM.
A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.
A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
The magnitude of INBREEDING in humans.
The cognitive and affective processes which constitute an internalized moral governor over an individual's moral conduct.
Sense of awareness of self and of the environment.
Organic mental disorders in which there is impairment of the ability to maintain awareness of self and environment and to respond to environmental stimuli. Dysfunction of the cerebral hemispheres or brain stem RETICULAR FORMATION may result in this condition.
Devices used to assess the level of consciousness especially during anesthesia. They measure brain activity level based on the EEG.
General agreement or collective opinion; the judgment arrived at by most of those concerned.
Official statements of the finding or recommendations expressing the outcome from a conference sponsored by NIH.
Articles on conferences sponsored by NIH presenting summary statements representing the majority agreement of physicians, scientists, and other professionals convening for the purpose of reaching a consensus on a subject of interest. This heading is used for NIH consensus conferences as a means of scientific communication. In indexing it is viewed as a type of review article and as a tag for any article appearing in any publication of the NIH Office of Medical Applications of Research (OMAR).
A theoretical representative nucleotide or amino acid sequence in which each nucleotide or amino acid is the one which occurs most frequently at that site in the different sequences which occur in nature. The phrase also refers to an actual sequence which approximates the theoretical consensus. A known CONSERVED SEQUENCE set is represented by a consensus sequence. Commonly observed supersecondary protein structures (AMINO ACID MOTIFS) are often formed by conserved sequences.
Official statements of the findings or recommendations expressing the outcome of a meeting convened to evaluate current thought and research on a subject of interest.
Works that are about the concept of consensus statements or consensus development conferences, such as their general design or a means of scientific communication.
Documents describing a medical treatment or research project, including proposed procedures, risks, and alternatives, that are to be signed by an individual, or the individual's proxy, to indicate his/her understanding of the document and a willingness to undergo the treatment or to participate in the research.
Planned management, use, and preservation of energy resources.
The protection, preservation, restoration, and rational use of all resources in the total environment.
A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.
Drug treatment designed to further diminish the disease toward complete remission following INDUCTION CHEMOTHERAPY. It helps to consolidate the gains during induction chemotherapy and may be followed by MAINTENANCE CHEMOTHERAPY.
Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
The fundamental principles and laws adopted by an organization for the regulation and governing of its affairs.
The act of constricting.
The condition of an anatomical structure's being constricted beyond normal dimensions.
The aggregate business enterprise of building.
Supplies used in building.
Individuals referred to for expert or professional advice or services.
The promotion and support of consumers' rights and interests.
Behavior associated with the procurement of goods, services, or experiences.
Information intended for potential users of medical and healthcare services. There is an emphasis on self-care and preventive approaches as well as information for community-wide dissemination and use.
Organized groups of users of goods and services.
The sum total of measures taken and regulatory policies enacted to ensure the safe use of consumer products.
An act which constitutes the termination of a given instinctive behavior pattern or sequence.
RefSeq NM_141204
Arrest of cell locomotion or cell division when two cells come into contact.
Sterile solutions used to clean and disinfect contact lenses.
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
Hydrophilic contact lenses worn for an extended period or permanently.
Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.
Identification of those persons (or animals) who have had such an association with an infected person, animal, or contaminated environment as to have had the opportunity to acquire the infection.