iDrugBank

Caspase 8

MESHD053181

A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.

Synonyms

  • CAP4 Protease
  • FLICE Protein
  • MACH Protein
  • Mch5 Protease
  • Caspase-8
  • Procaspase-8
  • Procaspase 8
  • Pro-Caspase-8
  • Pro Caspase 8

Source last updated 2026-05-24T15:24:57.741Z