Caspase 2
MESHD053143
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
Synonyms
- Caspase-2
- ICH-1 Protease
- ICH 1 Protease
- Procaspase-2
- Procaspase 2
- Pro-Caspase-2
- Pro Caspase 2
- Caspase 2 Subunit p18
- Caspase 2 Subunit p13
- Caspase 2 Subunit p12
Source last updated 2026-05-24T15:24:57.741Z