B7-2 Antigen
MESHD051940
A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
Synonyms
- B7 2 Antigen
- Early T Cell Costimulatory Molecule 1
- Antigens, CD86
- CD86 Antigens
- Antigen, B7-2
- Antigen, B7 2
- B7-2 Costimulatory Molecule
- Costimulatory Molecule, B7-2
- CD86 Antigen
- Antigen, CD86
- B70 Costimulatory Molecule
- Costimulatory Molecule, B70
Source last updated 2026-05-24T15:24:57.741Z