iDrugBank

Cyclin-Dependent Kinase Inhibitor p27

MESHD050760

A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT KINASES during the CELL CYCLE. It interacts with active CYCLIN D complexed to CYCLIN-DEPENDENT KINASE 4 in proliferating cells, while in arrested cells it binds and inhibits CYCLIN E complexed to CYCLIN-DEPENDENT KINASE 2.

Synonyms

  • Cyclin Dependent Kinase Inhibitor p27
  • CDKN4 Protein
  • p27 CDK Inhibitor
  • CDK Inhibitor, p27
  • Cyclin-Dependent Kinase Inhibitor 1B
  • Cyclin Dependent Kinase Inhibitor 1B
  • CDKN1B Protein
  • p27Kip1 Protein
  • CDK Inhibitor p27
  • p27, CDK Inhibitor
  • p27 Kip1 Protein
  • Kip1 Protein, p27

Source last updated 2026-05-24T15:25:04.520Z