iDrugBank

Core Binding Factor Alpha 2 Subunit

MESHD050676

A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.

Synonyms

  • Acute Myeloid Leukemia 1 Protein
  • Core-Binding Factor Alpha 2 Protein
  • Core Binding Factor Alpha 2 Protein
  • Pebp2a2 Protein
  • Runt-Related Transcription Factor 1
  • Runt Related Transcription Factor 1
  • Runx1 Protein
  • Acute Myeloid Leukemia 1A Protein
  • AML1A Protein
  • Acute Myeloid Leukemia 1B Protein
  • AML1B Protein
  • Acute Myeloid Leukemia 1D Protein
  • AML1D Protein
  • Acute Myeloid Leukemia 1C Protein
  • AML1C Protein

Source last updated 2026-05-24T15:25:04.520Z