Core Binding Factor alpha Subunits
MESHD050657
A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.
Synonyms
- Polyomavirus Enhancer A Binding Protein 2
- Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
- Runt Domain Factor
- Runx Proteins
- Acute Myeloid Leukemia Proteins
- PEBP2A Transcription Factors
- Transcription Factors, PEBP2A
- Core Binding Factor alpha Proteins
Source last updated 2026-05-24T15:25:04.520Z