iDrugBank

Calgranulin A

MESHD040501

A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.

Synonyms

  • Cystic Fibrosis Antigen
  • Antigen, Cystic Fibrosis
  • 60B8-B Antigen
  • 60B8 B Antigen
  • Antigen, 60B8-B
  • CABP-P8
  • MRP8 Protein
  • Macrophage-Related Protein-8
  • Macrophage Related Protein 8
  • Myeloid Calcium-Binding Protein P8
  • Myeloid Calcium Binding Protein P8
  • MRP-8 Protein
  • MRP 8 Protein
  • S100 A8 Protein
  • A8 Protein, S100
  • S100A8 Protein
  • Leukocyte L1 Protein Light Chain

Source last updated 2026-05-24T15:25:13.889Z