iDrugBank

ATP Binding Cassette Transporter, Subfamily B, Member 1

MESHD020168

A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).

Synonyms

  • ABCB1 Protein
  • CD243 Antigen
  • Antigen, CD243
  • ATP Binding Cassette Transporter, Sub-Family B, Member 1
  • P-Glycoprotein
  • P Glycoprotein
  • MDR1 Protein
  • Multidrug Resistance Protein 1
  • ATP-Binding Cassette, Sub-Family B, Member 1
  • PGY-1 Protein
  • PGY 1 Protein
  • ATP-Dependent Translocase ABCB1
  • ABCB1, ATP-Dependent Translocase
  • ATP Dependent Translocase ABCB1
  • Translocase ABCB1, ATP-Dependent
  • MDR1B Protein
  • Protein, MDR1B
  • P-Glycoprotein 1
  • 1, P-Glycoprotein
  • P Glycoprotein 1

Source last updated 2026-05-24T15:25:36.043Z