Anti-Glomerular Basement Membrane Disease
MESHD019867
An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
Synonyms
- Anti Glomerular Basement Membrane Disease
- Goodpasture's Syndrome
- Goodpastures Syndrome
- Syndrome, Goodpasture's
- Goodpasture Syndrome
- Syndrome, Goodpasture
- Lung Purpura with Nephritis
- Anti-GBM Disease
- Anti GBM Disease
Source last updated 2026-05-24T15:25:39.786Z