iDrugBank

Cytochrome P-450 CYP11B2

MESHD019405

A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.

Synonyms

  • Cytochrome P 450 CYP11B2
  • CYP11B2
  • P450c11AS
  • Steroid 18-Hydroxylase
  • Steroid 18 Hydroxylase
  • Aldosterone Synthase
  • Aldosterone Synthase Cytochrome P-450
  • Aldosynthase
  • Cytochrome P450Aldo
  • CYP 11B2
  • Cytochrome P450 11B2
  • Cytochrome P-450c11AS
  • Cytochrome P 450c11AS
  • Corticosterone 18-monooxygenase
  • 18-monooxygenase, Corticosterone
  • Corticosterone 18 monooxygenase
  • Corticosterone 18-hydroxylase
  • 18-hydroxylase, Corticosterone
  • Corticosterone 18 hydroxylase

Source last updated 2026-05-24T15:25:39.786Z