iDrugBank

CD59 Antigens

MESHD018957

Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)

Synonyms

  • Antigens, CD59
  • Membrane Attack Complex Inhibition Factor
  • HRF20
  • MACIF
  • Membrane Inhibitor of Reactive Lysis
  • Homologous Restriction Factor 20
  • CD59 Antigen
  • Protectin

Source last updated 2026-05-24T15:25:44.093Z