Complement C8
MESHD003185
A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.
Synonyms
- C8, Complement
- C8 Complement
- Complement, C8
- Complement 8
- Complement Component 8
- Component 8, Complement
- Complement Component C8 alpha
- Complement Component C8 alpha Chain
- Complement Component C8 beta
- Complement Component C8 beta Chain
- Complement Component C8 gamma
- Complement Component C8 gamma Chain
Source last updated 2026-05-24T15:27:57.172Z