Cholesterol 7-alpha-Hydroxylase
MESHD002790
A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.
Synonyms
- Cholesterol 7 alpha Hydroxylase
- Cholesterol 7alpha-Hydroxylase
- Cholesterol 7alpha Hydroxylase
- Cholesterol-7-Hydroxylase
- Cholesterol 7 Hydroxylase
- Cytochrome P-450 CYP7
- Cytochrome P 450 CYP7
- CYP 7
- Cytochrome P450 7
- CYP7
- CYP 7A
- Cholesterol 7-alpha-Monooxygenase
- Cholesterol 7 alpha Monooxygenase
- CYP7A
Source last updated 2026-05-24T15:28:01.396Z