Cholesterol Side-Chain Cleavage Enzyme
MESHD002786
A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 cholesterol to C21 pregnenolone in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11A1 gene, catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.
Synonyms
- Cholesterol Side Chain Cleavage Enzyme
- Cytochrome P450 11A1
- Cytochrome P-450 CYP11A1
- Cytochrome P 450 CYP11A1
- Cholesterol Monooxygenase (Side-Chain-Cleaving)
- CYP11A1
- 20,22-Desmolase
- 20,22 Desmolase
- Cholesterol Desmolase
- Cytochrome P-450(scc)
- CYP 11A1
- Cytochrome P450scc
Source last updated 2026-05-24T15:28:01.396Z