iDrugBank

Cantharidin

MESHD002193

A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.

Synonyms

  • Cantharidine
  • Cantharides

Source last updated 2026-05-24T15:28:08.267Z