iDrugBank

Aromatase

MESHD001141

An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.

Synonyms

  • Estrogen Synthetase
  • Estrogen Synthase
  • Cytochrome P450 19
  • CYP19
  • Cytochrome P-450(AROM)
  • CYP 19
  • Cytochrome P-450 CYP19
  • Cytochrome P 450 CYP19
  • P450AROM
  • Androstenedione Aromatase
  • Aromatase, Androstenedione
  • CYP19 Protein
  • Protein, CYP19

Source last updated 2026-05-24T15:28:12.255Z