iDrugBank

Arachidonate 12-Lipoxygenase

MESHD001092

An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.

Synonyms

  • 12-Lipoxygenase, Arachidonate
  • Arachidonate 12 Lipoxygenase
  • 12-Lipoxygenase
  • 12 Lipoxygenase
  • Arachidonic Acid 12-Lipoxygenase
  • 12-Lipoxygenase, Arachidonic Acid
  • Arachidonic Acid 12 Lipoxygenase

Source last updated 2026-05-24T15:28:12.255Z