Adie Syndrome
MESHD000270
A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)
Synonyms
- Syndrome, Adie
- Poorly Reacting Pupils
- Poorly Reacting Pupil
- Pupil, Poorly Reacting
- Pupils, Poorly Reacting
- Adie's Syndrome
- Syndrome, Adie's
- Holmes-Adie Syndrome
- Holmes Adie Syndrome
- Syndrome, Holmes-Adie
Source last updated 2026-05-24T15:28:24.502Z