Cold Hypersensitivity

Recurrent attacks of maculopapular rash arthralgias, myalgias, fever, chills, and swelling of the extremities after exposure to cold that are associated with Familial Cold Autoinflammatory Syndrome 1, which is caused by mutations in the NLRP3 gene. OMIM: 120100

Source last updated 2026-05-24T15:29:45.539Z