Claudin-1
MESHD062445
An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.
Synonyms
- Claudin 1
Source last updated 2026-05-24T15:24:25.902Z