iDrugBank

Autoimmune Lymphoproliferative Syndrome

MESHD056735

Rare congenital lymphoid disorder due to mutations in certain Fas-Fas ligand pathway genes. Known causes include mutations in FAS, TNFSF6, NRAS, CASP8, and CASP10 proteins. Clinical features include LYMPHADENOPATHY; SPLENOMEGALY; and AUTOIMMUNITY.

Synonyms

  • Autoimmune Lymphoproliferative Syndromes
  • Lymphoproliferative Syndrome, Autoimmune
  • Lymphoproliferative Syndromes, Autoimmune
  • Syndrome, Autoimmune Lymphoproliferative
  • Syndromes, Autoimmune Lymphoproliferative
  • Canale Smith Syndrome
  • Syndrome, Canale Smith
  • Canale-Smith Syndrome
  • Canale-Smith Syndromes
  • Syndrome, Canale-Smith
  • Syndromes, Canale-Smith
  • Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant
  • Autoimmune Lymphoproliferative Syndrome Type 2B
  • Autoimmune Lymphoproliferative Syndrome, Type IIb
  • Caspase-8 Deficiency
  • Caspase-8 Deficiencies
  • Deficiencies, Caspase-8
  • Deficiency, Caspase-8
  • Caspase 8 Deficiency
  • Caspase 8 Deficiencies
  • Deficiencies, Caspase 8
  • Deficiency, Caspase 8
  • Autoimmune Lymphoproliferative Syndrome Type 2B (ALPS2B)
  • Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant

Source last updated 2026-05-24T15:24:38.588Z