iDrugBank

Caspase 10

MESHD053455

A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

Synonyms

  • Caspase-10
  • Caspase 10a
  • Caspase 10-a
  • Caspase 10 a
  • Mch4 Protease
  • Protease, Mch4
  • Caspase 10c
  • Caspase 10-c
  • Caspase 10 c
  • Caspase 10d
  • Caspase 10-d
  • Caspase 10 d

Source last updated 2026-05-24T15:24:51.397Z