iDrugBank

Cyclin-Dependent Kinase 2

MESHD051357

A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.

Synonyms

  • Cyclin Dependent Kinase 2
  • p33cdk2 Kinase
  • CDK2 Protein
  • Cdc2-Related Protein Kinase
  • Cdc2 Related Protein Kinase
  • Cdk2 Protein Kinase

Source last updated 2026-05-24T15:24:57.741Z