iDrugBank

Complement C1 Inhibitor Protein

MESHD050718

An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.

Synonyms

  • C1 Esterase Inhibitor
  • Esterase Inhibitor, C1
  • C1-Inhibitor Protein
  • C1 Inhibitor Protein
  • C1-INH Protein
  • C1 INH Protein
  • Plasma Protease C1 Inhibitor
  • Complement C1-Inhibitor Protein
  • Serpin G1
  • Serpin Family G Member 1
  • SERPING1

Source last updated 2026-05-24T15:25:04.520Z