iDrugBank

4-Quinolones

MESHD042462

QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.

Synonyms

  • 4 Quinolones
  • 4-Quinolone
  • 4 Quinolone
  • 4-Quinolinone
  • 4 Quinolinone
  • 4-Oxoquinolines
  • 4 Oxoquinolines
  • 4-Quinolinones
  • 4 Quinolinones
  • 4-Oxoquinoline
  • 4 Oxoquinoline

Source last updated 2026-05-24T15:25:13.889Z