iDrugBank

Carboxypeptidase B2

MESHD025901

A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.

Synonyms

  • Arginine Carboxypeptidase
  • Carboxypeptidase R
  • Carboxypeptidase B2, Plasma
  • Plasma Carboxypeptidase B2
  • Thrombin-Activatable Fibrinolysis Inhibitor
  • Thrombin Activatable Fibrinolysis Inhibitor
  • Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
  • Carboxypeptidase U
  • Procarboxypeptidase U
  • Plasma Procarboxypeptidase B

Source last updated 2026-05-24T15:25:24.801Z