iDrugBank

AT-Hook Motifs

MESHD024761

DNA-binding motifs, first described in one of the HMGA PROTEINS: HMG-I(Y) PROTEIN. They consist of positively charged sequences of nine amino acids centered on the invariant tripeptide glycine-arginine-proline. They act to fasten the protein to an AT RICH SEQUENCE in the DNA.

Synonyms

  • AT-Hook Motif
  • AT Hook Motifs
  • Motif, AT-Hook
  • Motifs, AT-Hook
  • AT Hooks
  • AT Hook
  • Hook, AT
  • Hooks, AT
  • AT Hook Motif
  • Motif, AT Hook
  • Motifs, AT Hook

Source last updated 2026-05-24T15:25:24.801Z