iDrugBank

Antimicrobial Cationic Peptides

MESHD023181

Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.

Synonyms

  • Cationic Peptides, Antimicrobial
  • Peptides, Antimicrobial Cationic
  • Cationic Host Defense Peptides
  • Cationic Antimicrobial Peptide
  • Antimicrobial Peptide, Cationic
  • Peptide, Cationic Antimicrobial
  • Cationic Antimicrobial Peptides
  • Antimicrobial Peptides, Cationic
  • Peptides, Cationic Antimicrobial
  • Microbicidal Cationic Proteins
  • Cationic Proteins, Microbicidal
  • Proteins, Microbicidal Cationic
  • Amphipathic Cationic Antimicrobial Peptides
  • Host Defense Peptides
  • Defense Peptides, Host
  • Peptides, Host Defense
  • Host Defense Peptide
  • Defense Peptide, Host
  • Peptide, Host Defense

Source last updated 2026-05-24T15:25:31.844Z