Bulbar Palsy, Progressive
MESHD010244
A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)
Synonyms
- Bulbar Palsies, Progressive
- Palsies, Progressive Bulbar
- Palsy, Progressive Bulbar
- Progressive Bulbar Palsies
- Childhood Progressive Bulbar Palsy
- Progressive Bulbar Palsy of Childhood
- Bulbar Palsy, Progressive, Of Childhood
- Fazio-Londe Syndrome
- Fazio Londe Syndrome
- Syndrome, Fazio-Londe
- Fazio-Londe Disease
- Disease, Fazio-Londe
- Fazio Londe Disease
- Fazio-Londe's Disease
- Disease, Fazio-Londe's
- Fazio Londe's Disease
- Fazio-Londe's Syndrome
- Fazio Londe's Syndrome
- Syndrome, Fazio-Londe's
- Bulbar Palsy
- Bulbar Palsies
- Palsies, Bulbar
- Palsy, Bulbar
- Paralysis, Bulbar
- Bulbar Paralyses
- Bulbar Paralysis
Source last updated 2026-05-24T15:26:52.993Z