iDrugBank

Buprenorphine

MESHD002047

A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.

Synonyms

  • Subutex
  • Temgésic
  • Buprex
  • Temgesic
  • Buprenorphine Hydrochloride
  • Hydrochloride, Buprenorphine
  • 6029-M
  • 6029M
  • 6029 M
  • RX-6029-M
  • RX6029M
  • RX 6029 M
  • Buprenex
  • Prefin

Source last updated 2026-05-24T15:28:08.267Z