5-Aminolevulinate Synthetase
MESHD000624
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.
Synonyms
- 5 Aminolevulinate Synthetase
- Synthetase, 5-Aminolevulinate
- Aminolevulinic Acid Synthetase
- Acid Synthetase, Aminolevulinic
- Synthetase, Aminolevulinic Acid
- delta-Aminolevulinate Synthase
- delta Aminolevulinate Synthase
- Synthase, delta-Aminolevulinate
- delta-Aminolevulinic Acid Synthetase
- Acid Synthetase, delta-Aminolevulinic
- delta Aminolevulinic Acid Synthetase
- Synthetase, delta-Aminolevulinic Acid
- 5-Aminolevulinate Synthase
- 5 Aminolevulinate Synthase
- Synthase, 5-Aminolevulinate
Source last updated 2026-05-24T15:28:18.691Z